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Juxta-articular chondroma Kaposi's Sarcoma Large cell lymphoma, Leimyosarcoma, Leiomyosarcoma, Letterer-Siwe disease, Leukemia, Low-grade intramedullary osteogenic sarcoma, Lumbosacral lipoma, Lymphangioma, Lymphangiomatosis, Lymphoma, Lymphoma pseudotumor (Actual: radiation osteitis), Lymphoma pseudotumor (Actual: stress fracture), Lymphoma with secondary osteogenic sarcoma Maffucci's Syndrome, Maligant fibrous histiocytoma pseudotumor (Actual: Hematoma), Malignant fibrous histiocytoma (MFH).
Osteogenic sarcoma, low-grade intramedullary - Distal femur - Macrosection
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Osteogenic sarcoma, low-grade intramedullary - Distal femur - Macrosection
  • Case ID: 114
  • Classic Case: true
  • Diagnosis: Osteogenic sarcoma, low-grade intramedullary
  • Category: Bone Tumors
  • Category Type: Osteoid-forming
  • Category Sub Type: Malignant
  • Location: Distal femur
  • Age: 63
  • Sex: F
  • Treatment: Total knee arthroplasty
  • Image ID: 1420
  • Image Type: Macrosection
  • Images relating to this case: 955 , 1417 , 1418 , 1419 , 1420, 1421 , 1422 .

This patient had a wide local resection and a prosthetic reconstruction with a rotating hinge total knee device. This macrosection of the distal femoral metaphysis shows diffuse infiltrative tumor activity filling the entire medullary canal with no evidence of normal fatty marrow. There is some evidence of cortical erosion and permeation that would suggest a low-grade neoplasm such as a chondrosarcoma or osteosarcoma. This pciture is also compatible with fibrous dysplasia.


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