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Hodgkin's lymphoma - Lumbar spine - Photomicrograph
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Hodgkin's lymphoma - Lumbar spine - Photomicrograph
  • Case ID: 179
  • Diagnosis: Hodgkin's lymphoma
  • Category: Bone Tumors
  • Category Type: Round cell
  • Category Sub Type: Malignant
  • Location: Lumbar spine
  • Age: 40
  • Sex: M
  • Treatment: Chemotherapy
  • Image ID: 1730
  • Image Type: Photomicrograph
  • Images relating to this case: 1729 , 1730.

A percutaneous needle biopsy of the vertebral body was carried out and this low power photomicrograph shows extensive lymphocytic infiltration throughout the lesion. There is a very large histiocytic-appearing cell in the central area with a double nuclear appearance, quite characteristic of the so-called Reed-Sternberg cell, which is diagnostic of Hodgkin's lymphoma. In this case, the patient was staged and found to have no other evidence of disease which gave him an excellent prognosis for long term survival. He underwent minimal systemic chemotherapy; no radiation therapy was necessary because of the bone appeared strong with little chance for pathological compression fracture. Likewise, no surgical intervention was indicated because of the strong appearance of the lumbar vertebra.


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