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Juxta-articular chondroma Kaposi's Sarcoma Large cell lymphoma, Leimyosarcoma, Leiomyosarcoma, Letterer-Siwe disease, Leukemia, Low-grade intramedullary osteogenic sarcoma, Lumbosacral lipoma, Lymphangioma, Lymphangiomatosis, Lymphoma, Lymphoma pseudotumor (Actual: radiation osteitis), Lymphoma pseudotumor (Actual: stress fracture), Lymphoma with secondary osteogenic sarcoma Maffucci's Syndrome, Maligant fibrous histiocytoma pseudotumor (Actual: Hematoma), Malignant fibrous histiocytoma (MFH).
Osteogenic sarcoma, multicentric - Multiple skeletal sites - Photomicrograph
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Osteogenic sarcoma, multicentric - Multiple skeletal sites - Photomicrograph
  • Case ID: 539
  • Diagnosis: Osteogenic sarcoma, multicentric
  • Category: Bone Tumors
  • Category Type: Osteoid-forming
  • Category Sub Type: Malignant
  • Location: Multiple skeletal sites
  • Age: 16
  • Sex: F
  • Treatment: Total knee arthroplasty
  • Image ID: 3304
  • Image Type: Photomicrograph
  • Images relating to this case: 3299 , 3300 , 3301 , 3302 , 3303 , 3304, 3305 , 3306 , 3307 .

Low power photomicrograph from the biopsy of the tibia shows malignant osteoid being formed by aggressive -appearing osteoblasts. The diagnosis of multicentric osteogenic sarcoma was made. The patient was placed on chemotherapy and, at a later date, a resection of the proximal tibia and total knee arthroplasty was performed.


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